Programmatic e-mail refers to the automated process of sending targeted and personalized emails to a specific audience, based on data and algorithms. This method allows for the optimization of email campaigns by utilizing real-time data and machine learning to deliver the right message, to the right person, at the right time. Programmatic e-mail eliminates the need for manual segmentation and allows for a more efficient and effective way of reaching customers, resulting in higher engagement and conversion rates. It combines the power of technology with the art of communication to deliver a seamless and personalized email experience for both the sender and the recipient.